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Image Search Results


Selected compilation of drugs in clinical trials whose mechanisms of action may involve modulation of macrophages/TAMs

Journal: Advanced drug delivery reviews

Article Title: Progress in tumor-associated macrophage (TAM)-targeted therapeutics

doi: 10.1016/j.addr.2017.04.010

Figure Lengend Snippet: Selected compilation of drugs in clinical trials whose mechanisms of action may involve modulation of macrophages/TAMs

Article Snippet: Pexidartinib/PLX3397 (Oral c-fms/KIT/FLT3 tyrosine kinase inhibitor) , Centre Leon Berard and Plexxikon, AstraZeneca , 1 Ongoing , Advanced/metastatic colorectal or pancreatic cancer , With Durvalumab (Anti-PD-L1 antibody) , NCT02777710 , May 12, 2016.

Techniques: Clinical Proteomics, Mutagenesis, Inhibition, Variant Assay